There are
237 mi
from Knoxville, TN to Jeffersontown, KY
That's the driving distance. It would take 4 hours 21 mins to go from Knoxville, Tennessee to Jeffersontown, Kentucky.
The flight distance (direct flight from Knoxville, TN to Jeffersontown, KY) is 178.95 mi.
237 mi = 381.25 kms