Miles between Knoxville, TN and Greenville, SC

There are
168 mi
from Knoxville, TN to Greenville, SC

That's the driving distance. It would take 3 hours 30 mins to go from Knoxville, Tennessee to Greenville, South Carolina.

The flight distance (direct flight from Knoxville, TN to Greenville, SC) is 115.12 mi.

168 mi = 270.37 kms