Miles between Knoxville, TN and Gainesville, FL

There are
533 mi
from Knoxville, TN to Gainesville, FL

That's the driving distance. It would take 10 hours 3 mins to go from Knoxville, Tennessee to Gainesville, Florida.

The flight distance (direct flight from Knoxville, TN to Gainesville, FL) is 445.63 mi.

533 mi = 858.42 kms