There are
329 mi
from Knoxville, TN to Evansville, IN
That's the driving distance. It would take 6 hours 5 mins to go from Knoxville, Tennessee to Evansville, Indiana.
The flight distance (direct flight from Knoxville, TN to Evansville, IN) is 244.75 mi.
329 mi = 529.15 kms