Miles between Knoxville, TN and Defiance, OH

There are
423 mi
from Knoxville, TN to Defiance, OH

That's the driving distance. It would take 8 hours 11 mins to go from Knoxville, Tennessee to Defiance, Ohio.

The flight distance (direct flight from Knoxville, TN to Defiance, OH) is 368.59 mi.

423 mi = 680.48 kms