Miles between Knoxville, TN and Charleston, SC

There are
373 mi
from Knoxville, TN to Charleston, SC

That's the driving distance. It would take 7 hours 8 mins to go from Knoxville, Tennessee to Charleston, South Carolina.

The flight distance (direct flight from Knoxville, TN to Charleston, SC) is 316.44 mi.

373 mi = 599.88 kms