There are
2,099 mi
from Knoxville, TN to Cathedral City, CA
That's the driving distance. It would take 1 day 12 hours to go from Knoxville, Tennessee to Cathedral City, California.
The flight distance (direct flight from Knoxville, TN to Cathedral City, CA) is 1,842.48 mi.
2,099 mi = 3,377.34 kms