Miles between Knoxville, TN and Bluffton, SC

There are
406 mi
from Knoxville, TN to Bluffton, SC

That's the driving distance. It would take 7 hours 47 mins to go from Knoxville, Tennessee to Bluffton, South Carolina.

The flight distance (direct flight from Knoxville, TN to Bluffton, SC) is 311.15 mi.

406 mi = 652.96 kms