There are
2,166 mi
from Knoxville, TN to Azusa, CA
That's the driving distance. It would take 1 day 13 hours to go from Knoxville, Tennessee to Azusa, California.
The flight distance (direct flight from Knoxville, TN to Azusa, CA) is 1,916.96 mi.
2,166 mi = 3.22 kms