There are
2,325 mi
from Knoxville, TN to Arroyo Grande, CA
That's the driving distance. It would take 1 day 17 hours to go from Knoxville, Tennessee to Arroyo Grande, California.
The flight distance (direct flight from Knoxville, TN to Arroyo Grande, CA) is 2,050.27 mi.
2,325 mi = 3.22 kms