There are
2,457 mi
from Knoxville, TN to Antioch, CA
That's the driving distance. It would take 1 day 19 hours to go from Knoxville, Tennessee to Antioch, California.
The flight distance (direct flight from Knoxville, TN to Antioch, CA) is 2,081.35 mi.
2,457 mi = 3.22 kms