There are
165 mi
from Kalamazoo, MI to Des Plaines, IL
That's the driving distance. It would take 3 hours 20 mins to go from Kalamazoo, Michigan to Des Plaines, Illinois.
The flight distance (direct flight from Kalamazoo, MI to Des Plaines, IL) is 118.94 mi.
165 mi = 265.15 kms