There are
316 mi
from Kalamazoo, MI to Ashtabula, OH
That's the driving distance. It would take 6 hours to go from Kalamazoo, Michigan to Ashtabula, Ohio.
The flight distance (direct flight from Kalamazoo, MI to Ashtabula, OH) is 247.75 mi.
316 mi = 508.45 kms