There are
337 mi
from Kalamazoo, MI to Appleton, WI
That's the driving distance. It would take 6 hours 34 mins to go from Kalamazoo, Michigan to Appleton, Wisconsin.
The flight distance (direct flight from Kalamazoo, MI to Appleton, WI) is 196.88 mi.
337 mi = 542.11 kms