There are
2,257 mi
from Johnson City, TN to Palmdale, CA
That's the driving distance. It would take 1 day 15 hours to go from Johnson City, Tennessee to Palmdale, California.
The flight distance (direct flight from Johnson City, TN to Palmdale, CA) is 2,005.11 mi.
2,257 mi = 3,631.57 kms