There are
926 mi
from Jacksonville, NC to Creve Coeur, MO
That's the driving distance. It would take 17 hours 55 mins to go from Jacksonville, North Carolina to Creve Coeur, Missouri.
The flight distance (direct flight from Jacksonville, NC to Creve Coeur, MO) is 767.77 mi.
926 mi = 1,489.59 kms