Miles between Jacksonville, FL and Greenville, SC

There are
388 mi
from Jacksonville, FL to Greenville, SC

That's the driving distance. It would take 7 hours 5 mins to go from Jacksonville, Florida to Greenville, South Carolina.

The flight distance (direct flight from Jacksonville, FL to Greenville, SC) is 315.27 mi.

388 mi = 624.23 kms