Miles between Jackson, MS and Sikeston, MO

There are
352 mi
from Jackson, MS to Sikeston, MO

That's the driving distance. It would take 6 hours 23 mins to go from Jackson, Mississippi to Sikeston, Missouri.

The flight distance (direct flight from Jackson, MS to Sikeston, MO) is 318.12 mi.

352 mi = 566.70 kms