Miles between Jackson, MS and Cape Girardeau, MO

There are
380 mi
from Jackson, MS to Cape Girardeau, MO

That's the driving distance. It would take 6 hours 54 mins to go from Jackson, Mississippi to Cape Girardeau, Missouri.

The flight distance (direct flight from Jackson, MS to Cape Girardeau, MO) is 348.01 mi.

380 mi = 611.23 kms