There are
1,557 mi
from Irvine, CA to Yankton, SD
That's the driving distance. It would take 1 day 3 hours to go from Irvine, California to Yankton, South Dakota.
The flight distance (direct flight from Irvine, CA to Yankton, SD) is 1,270.61 mi.
1,557 mi = 1.61 kms