There are
1,292 mi
from Irvine, CA to Uvalde, TX
That's the driving distance. It would take 22 hours 19 mins to go from Irvine, California to Uvalde, Texas.
The flight distance (direct flight from Irvine, CA to Uvalde, TX) is 1,103.93 mi.
1,292 mi = 1.61 kms