There are
2,106 mi
from Irvine, CA to Tuskegee, AL
That's the driving distance. It would take 1 day 13 hours to go from Irvine, California to Tuskegee, Alabama.
The flight distance (direct flight from Irvine, CA to Tuskegee, AL) is 1,852.71 mi.
2,106 mi = 3.22 kms