There are
2,541 mi
from Irvine, CA to Tonawanda, NY
That's the driving distance. It would take 1 day 21 hours to go from Irvine, California to Tonawanda, New York.
The flight distance (direct flight from Irvine, CA to Tonawanda, NY) is 2,184.28 mi.
2,541 mi = 3.22 kms