There are
3,091 mi
from Irvine, CA to South Portland, ME
That's the driving distance. It would take 2 days 7 hours to go from Irvine, California to South Portland, Maine.
The flight distance (direct flight from Irvine, CA to South Portland, ME) is 2,618.11 mi.
3,091 mi = 4,974.98 kms