There are
1,666 mi
from Irvine, CA to Sioux Falls, SD
That's the driving distance. It would take 1 day 4 hours to go from Irvine, California to Sioux Falls, South Dakota.
The flight distance (direct flight from Irvine, CA to Sioux Falls, SD) is 1,321.53 mi.
1,666 mi = 1.61 kms