There are
2,444 mi
from Irvine, CA to Roanoke, VA
That's the driving distance. It would take 1 day 19 hours to go from Irvine, California to Roanoke, Virginia.
The flight distance (direct flight from Irvine, CA to Roanoke, VA) is 2,130.03 mi.
2,444 mi = 3.22 kms