There are
2,537 mi
from Irvine, CA to North Tonawanda, NY
That's the driving distance. It would take 1 day 21 hours to go from Irvine, California to North Tonawanda, New York.
The flight distance (direct flight from Irvine, CA to North Tonawanda, NY) is 2,184.11 mi.
2,537 mi = 3.22 kms