There are
2,166 mi
from Irvine, CA to Nicholasville, KY
That's the driving distance. It would take 1 day 14 hours to go from Irvine, California to Nicholasville, Kentucky.
The flight distance (direct flight from Irvine, CA to Nicholasville, KY) is 1,874.53 mi.
2,166 mi = 3.22 kms