There are
1,333 mi
from Irvine, CA to Lexington, NE
That's the driving distance. It would take 23 hours 10 mins to go from Irvine, California to Lexington, Nebraska.
The flight distance (direct flight from Irvine, CA to Lexington, NE) is 1,104.58 mi.
1,333 mi = 2,145.52 kms