There are
746 mi
from Irvine, CA to Las Cruces, NM
That's the driving distance. It would take 13 hours 9 mins to go from Irvine, California to Las Cruces, New Mexico.
The flight distance (direct flight from Irvine, CA to Las Cruces, NM) is 645.78 mi.
746 mi = 1,200.12 kms