There are
722 mi
from Irvine, CA to Klamath Falls, OR
That's the driving distance. It would take 13 hours 21 mins to go from Irvine, California to Klamath Falls, Oregon.
The flight distance (direct flight from Irvine, CA to Klamath Falls, OR) is 628.63 mi.
722 mi = 1,161.70 kms