There are
1,750 mi
from Irvine, CA to Jefferson City, MO
That's the driving distance. It would take 1 day 6 hours to go from Irvine, California to Jefferson City, Missouri.
The flight distance (direct flight from Irvine, CA to Jefferson City, MO) is 1,464.05 mi.
1,750 mi = 1.61 kms