There are
1,352 mi
from Irvine, CA to Guthrie, OK
That's the driving distance. It would take 23 hours 29 mins to go from Irvine, California to Guthrie, Oklahoma.
The flight distance (direct flight from Irvine, CA to Guthrie, OK) is 1,163.71 mi.
1,352 mi = 2,175.76 kms