There are
2,504 mi
from Irvine, CA to Gulfport, FL
That's the driving distance. It would take 1 day 20 hours to go from Irvine, California to Gulfport, Florida.
The flight distance (direct flight from Irvine, CA to Gulfport, FL) is 2,113.94 mi.
2,504 mi = 3.22 kms