There are
2,634 mi
from Irvine, CA to Greenville, NC
That's the driving distance. It would take 1 day 22 hours to go from Irvine, California to Greenville, North Carolina.
The flight distance (direct flight from Irvine, CA to Greenville, NC) is 2,285.68 mi.
2,634 mi = 3.22 kms