There are
1,800 mi
from Irvine, CA to Greenville, MS
That's the driving distance. It would take 1 day 7 hours to go from Irvine, California to Greenville, Mississippi.
The flight distance (direct flight from Irvine, CA to Greenville, MS) is 1,535.21 mi.
1,800 mi = 1.61 kms