There are
1,826 mi
from Irvine, CA to Festus, MO
That's the driving distance. It would take 1 day 8 hours to go from Irvine, California to Festus, Missouri.
The flight distance (direct flight from Irvine, CA to Festus, MO) is 1,558.18 mi.
1,826 mi = 1.61 kms