There are
1,450 mi
from Irvine, CA to Brenham, TX
That's the driving distance. It would take 1 day 1 hour to go from Irvine, California to Brenham, Texas.
The flight distance (direct flight from Irvine, CA to Brenham, TX) is 1,275.65 mi.
1,450 mi = 1.61 kms