There are
342 mi
from Irvine, CA to Avondale, AZ
That's the driving distance. It would take 6 hours 11 mins to go from Irvine, California to Avondale, Arizona.
The flight distance (direct flight from Irvine, CA to Avondale, AZ) is 313.93 mi.
342 mi = 550.52 kms