There are
555 mi
from Iowa City, IA to Nicholasville, KY
That's the driving distance. It would take 10 hours 16 mins to go from Iowa City, Iowa to Nicholasville, Kentucky.
The flight distance (direct flight from Iowa City, IA to Nicholasville, KY) is 452.23 mi.
555 mi = 893.44 kms