There are
1,762 mi
from Indio, CA to Edwardsville, IL
That's the driving distance. It would take 1 day 6 hours to go from Indio, California to Edwardsville, Illinois.
The flight distance (direct flight from Indio, CA to Edwardsville, IL) is 1,499.11 mi.
1,762 mi = 1.61 kms