Miles between Indianapolis, IN and Simpsonville, SC

There are
517 mi
from Indianapolis, IN to Simpsonville, SC

That's the driving distance. It would take 10 hours 18 mins to go from Indianapolis, Indiana to Simpsonville, South Carolina.

The flight distance (direct flight from Indianapolis, IN to Simpsonville, SC) is 408.48 mi.

517 mi = 832.64 kms