Miles between Indianapolis, IN and Sikeston, MO

There are
329 mi
from Indianapolis, IN to Sikeston, MO

That's the driving distance. It would take 6 hours 2 mins to go from Indianapolis, Indiana to Sikeston, Missouri.

The flight distance (direct flight from Indianapolis, IN to Sikeston, MO) is 272.88 mi.

329 mi = 528.93 kms