Miles between Independence, MO and Sikeston, MO

There are
371 mi
from Independence, MO to Sikeston, MO

That's the driving distance. It would take 7 hours to go from Independence, Missouri to Sikeston, Missouri.

The flight distance (direct flight from Independence, MO to Sikeston, MO) is 304.12 mi.

371 mi = 597.47 kms