Miles between Independence, MO and Cape Girardeau, MO

There are
341 mi
from Independence, MO to Cape Girardeau, MO

That's the driving distance. It would take 6 hours 30 mins to go from Independence, Missouri to Cape Girardeau, Missouri.

The flight distance (direct flight from Independence, MO to Cape Girardeau, MO) is 293.07 mi.

341 mi = 549.24 kms