Miles between Huntsville, AL and Simpsonville, SC

There are
321 mi
from Huntsville, AL to Simpsonville, SC

That's the driving distance. It would take 6 hours 35 mins to go from Huntsville, Alabama to Simpsonville, South Carolina.

The flight distance (direct flight from Huntsville, AL to Simpsonville, SC) is 245.95 mi.

321 mi = 515.92 kms