There are
1,080 mi
from Hilton Head Island, SC to Gainesville, TX
That's the driving distance. It would take 20 hours 15 mins to go from Hilton Head Island, South Carolina to Gainesville, Texas.
The flight distance (direct flight from Hilton Head Island, SC to Gainesville, TX) is 954.02 mi.
1,080 mi = 1,737.65 kms