There are
2,123 mi
from Hayward, CA to Sikeston, MO
That's the driving distance. It would take 1 day 13 hours to go from Hayward, California to Sikeston, Missouri.
The flight distance (direct flight from Hayward, CA to Sikeston, MO) is 1,778.38 mi.
2,123 mi = 3.22 kms