There are
1,862 mi
from Hawthorne, CA to Sikeston, MO
That's the driving distance. It would take 1 day 8 hours to go from Hawthorne, California to Sikeston, Missouri.
The flight distance (direct flight from Hawthorne, CA to Sikeston, MO) is 1,626.77 mi.
1,862 mi = 1.61 kms