There are
1,321 mi
from Harlingen, TX to Nicholasville, KY
That's the driving distance. It would take 1 day to go from Harlingen, Texas to Nicholasville, Kentucky.
The flight distance (direct flight from Harlingen, TX to Nicholasville, KY) is 1,112.65 mi.
1,321 mi = 2,125.63 kms